Strains
BossBiotics
These clinically studied strains support oral wellness and microbiome balance. Selected specifically to support oral health maintenance.*
Made in the USA
Streptococcus salivarius (K12 & M18)
A clinically studied probiotic strain that supports fresh breath confidence by helping maintain balanced oral flora.* This strain supports natural oral processes and promotes a healthy oral environment.* K12 is particularly effective for supporting breath freshness, while M18 offers additional benefits for supporting oral cleanliness and gum wellness.* Studies show optimal results when incorporated into regular oral care routines, with noticeable improvements in as little as four weeks.*
Lactobacillus reuteri (DSM 17938 & ATCC PTA 5289)
Supports gum wellness, breath freshness, and oral health maintenance.* This strain promotes natural oral balance and supports comfortable gum health.* Clinical studies demonstrate its ability to support gum wellness by promoting healthy oral flora.* Additionally, it supports oral health by helping maintain natural pH levels in saliva.* Regular use has been shown to support breath freshness within 14 days.*
Lactobacillus paracasei (SD1)
Particularly effective in supporting oral health and promoting natural tooth wellness.* It works by supporting balanced oral flora and healthy bacterial levels.* Consistent use for three to four weeks has shown notable benefits for overall oral wellness.*
Lactobacillus salivarius
Emerging research supports its role in promoting overall oral wellness by helping maintain balanced oral flora.* This strain supports natural oral processes and contributes to oral health maintenance.* Preliminary research indicates positive changes in oral bacteria balance after two weeks of use, supporting overall oral wellness.*
CLINICAL STUDIES
- A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters - PubMed
- Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial - PubMed
- Antimicrobial activity of Streptococcus salivarius K12 on bacteria involved in oral malodour - PubMed
- The rationale and potential for the reduction of oral malodour using Streptococcus salivarius probiotics - PubMed
- A concerted probiotic activity to inhibit periodontitis-associated bacteria - PubMed
- The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis - PubMed
- Streptococcus salivarius inhibits immune activation by periodontal disease pathogens - PubMed
- Anti-inflammatory properties of Streptococcus salivarius, a commensal bacterium of the oral cavity and digestive tract - PubMed
- Clinical effect of Lactobacillus on the treatment of severe periodontitis and halitosis: A double-blinded, placebo-controlled, randomized clinical trial - PubMed
- Effect of the probiotic Lactobacilli reuteri (Prodentis) in the management of periodontal disease: a preliminary randomized clinical trial - PubMed
- Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study - PubMed
- Effectiveness of Probiotic Lozenges in Periodontal Management of Chronic Periodontitis Patients: Clinical and Immunological Study - PubMed
- Effect of chewing gums containing the probiotic bacterium Lactobacillus reuteri on oral malodour - PubMed
- Acid production in dental plaque after exposure to probiotic bacteria - PubMed
- Oral administration of Lactobacillus reuteri during the first year of life reduces caries prevalence in the primary dentition at 9 years of age - PubMed
- Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial - PubMed
- Effects of Lactobacillus salivarius WB21 combined with green tea catechins on dental caries, periodontitis, and oral malodor - PubMed
- The Effect of Lactobacillus salivarius SGL03 on Clinical and Microbiological Parameters in Periodontal Patients - PubMed
- Effect of Long-Term Consumption of Lactobacillus paracasei SD1 on Reducing Mutans streptococci and Caries Risk: A Randomized Placebo-Controlled Trial - PubMed
- Reducing mutans streptococci and caries development by Lactobacillus paracasei SD1 in preschool children: a randomized placebo-controlled trial - PubMed
- Efficacy of Probiotic Milk for Caries Regression in Preschool Children: A Multicenter Randomized Controlled Trial - PubMed
- Lactobacillus paracasei SD1, a novel probiotic, reduces mutans streptococci in human volunteers: a randomized placebo-controlled trial - PubMed
- Early intervention with probiotic Lactobacillus paracasei F19 has no long-term effect on caries experience - PubMed
- Probiotic Lactobacillus paracasei effect on cariogenic bacterial flora - PubMed
*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.