Strains
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Streptococcus salivarius (K12 & M18)
A powerful probiotic strain known for its ability to reduce bad breath (halitosis) by decreasing volatile sulfur compounds (VSCs) and inhibiting periodontal pathogens. It works by producing bacteriocins that suppress harmful bacteria and support immune homeostasis. K12 is particularly effective for combating halitosis, while M18 has additional benefits in reducing plaque and preventing gum disease. Studies show that its effectiveness increases when used after an antiseptic mouthwash to reset the oral microbiome, with noticeable results in as little as four weeks when taken as lozenges.
Lactobacillus reuteri (DSM 17938 & ATCC PTA 5289)
Offers significant benefits for reducing gum disease symptoms, bad breath, and cavity risk. It produces Reuterin, a potent antimicrobial peptide, and reduces inflammation by lowering pro-inflammatory cytokines. Clinical studies demonstrate its ability to improve gum health by reducing plaque and bleeding. Additionally, it helps prevent tooth decay by decreasing lactic acid levels in saliva. Chewing gum containing this strain has been shown to significantly lower bad breath levels within 14 days.
Lactobacillus paracasei (SD1)
Particularly effective in reducing the progression of cavities and promoting the remineralization of early tooth decay. It works by lowering the levels of Streptococcus mutans, a primary contributor to cavities. Consistent use for three to four weeks has shown notable benefits, especially in individuals with high levels of S. mutans.
Lactobacillus salivarius
Emerging evidence supporting its role in improving overall oral health by potentially reducing Streptococcus mutans levels. This strain produces antimicrobial peptides, though its effectiveness is not as well-established as other strains. Preliminary research indicates reductions in S. mutans after two weeks of lozenge use, suggesting potential for cavity prevention.
STUDIES
A concerted probiotic activity to inhibit periodontitis-associated bacteria - PubMed
Streptococcus salivarius inhibits immune activation by periodontal disease pathogens - PubMed
Acid production in dental plaque after exposure to probiotic bacteria - PubMed
Probiotic Lactobacillus paracasei effect on cariogenic bacterial flora - PubMed